Liquid Chromatography vs. Gas Chromatography: Which One Is More Widely Used?
Both liquid chromatography and gas chromatography have their strengths and weaknesses, and the choice between them often depends on what you’re analyzing. In terms of sheer versatility and wide applicability, liquid chromatography—particularly HPLC—takes the crown as the more widely used technique. It’s the go-to method in industries like pharmaceuticals, biotechnology, and food safety.
However, gas chromatography is still the top choice in specific niches, especially where volatile compounds are involved. So, what do I think? If you’re working with non-volatile, heat-sensitive samples, LC is the way to go. But if speed and sensitivity for volatile compounds are more critical, GC should be your tool of choice. What do you think—have you found yourself relying on one more than the other in your work?